Found 15 matching trials
Sapropterin in Individuals With Phenylketonuria
N/AInvestigators at Washington University will examine the effects of sapropte...
Location
Washington University
The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication
PHASE1This study will focus on people with claudication from peripheral arterial ...
Status
Active Not Recruiting
Location
UMASS Memorial Healthcare - University Campus
Trial of Kuvan in Lesch-Nyhan Disease
PHASE2To assess the possibility that treatment with Kuvan (a form of tetrahydrobi...
Location
UCSD Mitochondrial and Metabolic Disease Center
Study of Phenoptin to Increase Phenylalanine Tolerance in Phenylketonuric Children on a Phenylalanine-restricted Diet
PHASE3The primary objective of this trial is to evaluate the ability of Phenoptin...
Location
Multiple Locations
Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response
PHASE2The investigators will investigate the effect of blood phenylalanine on Kuv...
Location
Department of Biochemistry & Molecular Biology
The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)
N/AThe objective of the study is to determine whether Kuvan™ (sapropterin) imp...
Location
University of Missouri
The Effectiveness of Kuvan in Amish PKU Patients
PHASE4The purpose of this study is to determine if Amish patients with PKU show r...
Location
University Hospitals Cleveland Medical Center
Rhode Island Diastolic Dysfunction - Heart Failure
NATo study the hypothesis that treating patients with underlying diastolic dy...
Study of Kuvan Treatment in Adults With GTPCH Deficiency
PHASE1The purpose of this study is to identify the dose of Kuvan needed to normal...
Location
University of Utah
A Phase 1 Study to Evaluate Effects of Sapropterin Dihydrochloride on QTc Intervals in Healthy Adult Subjects
PHASE1Sapropterin dihydrochloride (subsequently referred to as sapropterin) (Kuva...
Location
PRACS Institute, Ltd.